Tracheobronchial Amyloidosis


Amyloidosis is a form of plasma cell dyscrasia of unknown etiology, pathologically characterized by the extracellular deposit of fibrils derived from the light chain of monoclonal immunoglobulin. The involvement of the airways is more common in primary amyloidosis and is classified into: tracheobronchial amyloidosis, nodular parenchymal, diffuse parenchymal. The tracheobronchial form is usually the most frequent and is characterized by the presence of multiple submucosal plaques or, more rarely, by pseudotumoral endobronchial masses. Symptoms in the initial phase may be silent, subsequently manifesting themselves with cough, dyspnea, hemoptysis.

DOI Code: 10.1285/i25327518v4i2p41

Keywords: amyloid substance; amyloidosis L and A; pseudotumoral plaques or masses of amyloid substance affecting the trachea and bronchi

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